1. The Signal
Wine Was Impersonating Something Your Brain Already Knows How to Make — Just Not Enough Of
GABA is the brain's primary inhibitory neurotransmitter. It's the signal that tells your nervous system the day is over. When it's working, the off-switch works. When it's depleted — which chronic stress reliably does — the off-switch requires outside help. Wine impersonates GABA's signal through alcohol's effect on the same receptor system. The calm that arrives with the first glass is real. It's just borrowed.
Borrowed calm comes with a repayment schedule. As the alcohol metabolizes, cortisol and adrenaline rebound above their baseline levels. That's the 3am wake-up. That's the heart already going before your brain knows why. The nervous system is paying back what the wine borrowed — with interest.
